研究業績

これまで発表した論文などを記しています

発表論文

2024

87. Takumi, S., Tomioka, M., Yunoki, Y., Eto, R., Komatsu, Y., Shiozaki, K., Komatsu, M. ; Microcystin-LR-induced epithelial-mesenchymal transition-like cells acquire resistance to multi-toxins. Toxicon. 238, 107592, 2024.

https://doi.org/10.1016/j.toxicon.2023.107592

2023

86. Sato, Y., Matsunaga, R., Tasumi, S., Mizuno, N., Nakane, M., Hosoya, S., Yamamto, A., Nakamura, O., Tsutsui, S., Shiozaki, K., Kikuchi, T. L-fucoside localization in the gills of the genus Takifugu and its possible implication in the parasitism of Heterobothrium okamotoi

(Monogenea: Diclidophoridae). Biochim. Biophys. Acta-Gen. Subj. 1867, 130467. 2023.

https://doi.org/10.1016/j.bbagen.2023.130467

85. Nishida, T., Horita, C., Imagawa, M., Hibarino, M., Tateno, S., Kubo, Y., Kawabe, M., Morishita, N., Endo, S., Shiozaki, K. Glucosyl hesperidin exhibits more potent anxiolytic activity than hesperidin accompanied by the attenuation of noradrenaline induction in a zebrafish model. Front. Pharmacol. 14, 1213252. 2023.

https://doi.org/10.3389/fphar.2023.1213252

84. Kawabe, M., Nishida, T., Takahashi, R., Inui, A., Shiozaki, K. Comparative study of the effects of the three kinds of Kampo-hozai: Ninjinyoeito, Hochuekkito, and Juzentaihoto on anxious and low sociability behavior using NPY-knockout zebrafish. Front. Pharmacol. 14, 1168229, 2023

https://doi.org/10.3389/fphar.2023.1168229

83. Hyodo, T., Honda, A., Yamate, S., Kubo, Y., Komatsu M., Shiozaki, K. Elucidation of the mechanism of nuclear localization of Mexican tetra Neu4 via bipartite nuclear localization signal and less conserved regions. Biochimie. 212, 123-134, 2023

https://doi.org/10.1016/j.biochi.2023.04.012

82. Takumi, S., Hashimoto, K., Tomioka, M., Sato, M., He, W., Komatsu, Y., Aoki, S., Ikeda, R., Shiozaki, K., Furukawa, T., Komatsu M. Acteoside from Conandron ramondioides reduces microcystin-LR cytotoxicity by inhibiting intracellular uptake mediated by OATP1B3. Planta Med. 89, 616-623, 2023

https://doi.org/10.1055/a-1978-8768

2022

81. Kawabe, M., Nishida, T., Horita, C., Ikeda, A., Takahashi, R., Inui, A., Shiozaki, K. Ninjinyoeito improves social behavior disorder in neuropeptide Y deficient zebrafish. Front. Pharmacol. 13, 905711, 2022

https://doi.org/10.3389/fphar.2022.905711

80. Ikeda, A., Yamasaki, C., Kubo, Y., Doi, Y., Komamizu, M., Komatsu, M., Shiozaki, K. Alteration of the neuronal and glial cell profiles in Neu1-deficient zebrafish. Glycoconj. J. 39, 499-512, 2022.

https://doi.org/10.1007/s10719-022-10074-8

79. Sahashi, D., Kubo, Y., Ishii, M., Ikeda, A., Yamasaki, C., Komatsu, M., Shiozaki, K. Neu1 deficiency increases the susceptibility of zebrafish to Edwardsiella piscicida infection via lysosomal dysfunction. Gene. 836, 146667, 2022

https://doi.org/10.1016/j.gene.2022.146667

78. Tran, TN., Vo, KL., Komatsu, M., Shiozaki, K. Involvement of N-acetylneuraminate cytidylyltransferase in Edwardsiella piscicida pathogenicity. Fish Shellfish Immunol. 124, 534-542, 2022.

https://doi.org/10.1016/j.fsi.2022.04.033

77. 塩﨑一弘：機能性研究におけるゼブラフィッシュの活用~第3の実験動物として~. 食品と科学. 64, 16-23, 2022

https://www.fujisan.co.jp/product/1227334/b/2217027/

76. Vo, KL., Tran, TN., Kubo, Y., Sahashi, D., Komatsu, M., Shiozaki, K. Enhancement of Edwardsiella piscicida infection, biofilm formation, and motility caused by N-acetylneuraminate lyase. Glycoconj. J. 39, 429-442, 2022.

https://doi.org/10.1007/s10719-022-10045-z

75. Takumi, S., Komatsu, Y., Domen, Y., Sumizawa, T., Shiozaki, K., Ishikawa, M., Komatsu, M., Hayashi, S., Yamada, S. Eel serum synergistically enhances growth of fish cell line GAKS.

Mem. Fac. Fish. Kagoshima Univ. 70, 1-8, 2022.

https://ir.kagoshima-u.ac.jp/?action=repository_uri&item_id=15984&file_id=16&file_no=1

2021

74. Kume, G., Shigemura, T., Okanishi, M., Hirai, J., Shiozaki, K., Ichinomiya, M., Komorita, T., Habano, A., Makino, F., Kobari, T. Distribution, feeding habits, and growth of Chub Mackerel, Scomber japonicus, larvae during a high-stock period in the Northern Satsunan area, Southern Japan.

Front. Mar. Sci. 8, 725227, 2021

https://doi.org/10.3389/fmars.2021.725227

73. Ikeda, A., Komamizu, M., Hayashi, A., Yamasaki, C., Okada, K., Kawabe, M., Komatsu, M., Shiozaki, K. Neu1 deficiency induces abnormal emotional behavior in zebrafish. Sci. Rep. 11, article NO:13477, 2021

https://doi.org/10.1038/s41598-021-92778-9

72. Oishi, K., Morise, M., Vo, KL., Tran, TN., Sahashi, D., Ueda-Wakamatsu, R., Nishimura, W., Komatsu, M., Shiozaki, K. Host lactosylceramide enhances Edwardsiella tarda infection. Cell Micobiol. 23, e13365, 2021

https://doi.org/10.1111/cmi.13365

71. Honda, A., Hayasaka, O., Mio, K., Fujimura, K., Kotani, T., Komatsu, M., Shiozaki, K. The involvement of Nile tilapia (Oreochromis niloticus) Neu4 sialidase in neural differentiation during early ontogenesis. Biochimie. 185, 105-116, 2021

https://doi.org/10.1016/j.biochi.2021.03.008

70. Kawabe, M., Hayashi, A., Komatsu, M., Inui, A., Shiozaki, K. Ninjinyoeito improves anxiety behavior in neuropeptide Y deficient zebrafish. Neuropeptides. 87, article NO:102136, 2021

https://doi.org/10.1016/j.npep.2021.102136

69. Tran, NDK., Waqalevu, V., Honda, A., Matsui, H., Nguen, XT., Sakaguchi, K., Kawaji, H., Ishikawa, M., Shiozaki, K., Kotani, T. Enrichment effects of fermented by-product of Shochu distillery on Brachionus plicatilis sp. rotifer and larviculture performance in Japanese flounder (Paralichthys olivaceus). Aquaculture. 535, article No:736352, 2021

https://doi.org/10.1016/j.aquaculture.2021.736352

68. Tran, NDK., Hayasaka, O., Matsui, H., Waqalevu, V., Honda, A., Nakajima. K., Yamashita, H., Ishikawa, M., Shiozaki, K., Kotani, T. Changes in early digestive tract morphology, enzyme expression and activity of Kawakawa tuna (Euthynnus affinis). Aquaculture. 530, article No:735935, 2021

https://doi.org/10.1016/j.aquaculture.2020.735935

67. Tran, NDK., Waqalevu, V., Honda, A., Shiozaki, K., Kotani, T. An integrative description of the digestive system morphology and function of Japanese flounder (Paralichthys olivaceus) during early ontogenetic development. Aquaculture. 531, article No: 735855, 2021

https://doi.org/10.1016/j.aquaculture.2020.735855

2020

66. Shiozaki, K., Uezono, K., Hirai, G., Honda, A., Minoda, M., Wakata R. Identification of novel fish sialidase genes responsible for KDN-cleaving activity. Glycoconj. J. 37. 745-753, 2020

https://doi.org/10.1007/s10719-020-09948-6

65. Okada, K., Takase, R., Hamaoka, Y., Honda, A., Ikeda, A., Hokazono, Y., Maeda, Y., Hayasaka, O., Kotani, T., Komatsu, M., Shiozaki, K. Establishment and characterization of Neu1-knockout zebrafish and its abnormal clinical phenotypes. Biochem. J. 477. 2841-2857, 2020

https://doi.org/10.1042/BCJ20200348

64. Matsui, H., Shiozaki, K., Okumura, Y., Ishikawa, M., Waqalevu, V., Hayasaka, O., Honda, A., Kotani, T., Effects of phosphorous deficiency of a microalga Nannochloropsis oculata on its fatty acid profiles and intracellular structure and the effectiveness in rotifer nutrition. Algal Res. 40. article No:101905, 2020

https://doi.org/10.1016/j.algal.2020.101905

63. Shiozaki, K, Kawabe, M., Karasuyama, K., Kurachi, T., Hayashi, A., Ataka, K., Iwai, H., Takeno, H., Hayasaka, O., Kotani, T., Komatsu, M., Inui, A., Neuropeptide Y deficiency induces anxiety-like behaviours in zebrafish (Danio rerio). Sci. Rep. 10. article NO:5913, 2020

https://doi.org/10.1038/s41598-020-62699-0

62. Honda, A., Chigwechokha, PK., Takase, R., Hayasaka, O., Fujimura, K., Kotani, T., Komatsu, M., Shiozaki, K., Novel Nile tilapia Neu1 sialidases: Molecular cloning and biochemical characterization of the sialidases Neu1a and Neu1b. Gene. 742. article:144538, 2020

https://doi.org/10.1016/j.gene.2020.144538

61. Oishi, K., Miyazaki, M., Takase, R., Chigwechokha, KP., Komatsu, M., Shiozaki, K., Regulation of triglyceride metabolism in medaka (Oryzias latipes) hepatocytes by Neu3a sialidase. Fish Physiol. Biochem. 46, 563-574, 2020

https://doi.org/10.1007/s10695-019-00730-6

60. Tran, NDK., Waqalevu, V., Honda, A., Shiozaki, K., Kotani, T., Comparative study on early digestive enzyme activity and expression in red sea bream (Pagrus major) fed on live feed and micro-diet. Aquaculture. 519, article:734721, 2020

https://doi.org/10.1016/j.aquaculture.2019.734721

2019

59. Vo, KL., Tsuzuki, T., Kamada-Futagami, Y., Chigwechokha KP., Honda, A., Oishi, K., Komatsu, M., Shiozaki, K., Desialylation by Edwardsiella tarda is the initial step in the regulation of its invasiveness. Biochem. J. 476, 3183-3196, 2019

https://doi.org/10.1042/BCJ20190367

58. Matsumoto, M., Kubota, T., Fujita, S., Shiozaki, K., Kishida, S., Yamamoto., A., Elucidation of the Interleukin 12 production mechanism during intracellular bacterial infection in amberjack, Seriola dumerili. Infect. Immun. 87, e00459-19, 2019

https://doi.org/10.1128/IAI.00459-19

57. Tran, NDK., Waqalevu, V., Honda, A., Shiozaki, K., Kotani, T., Early ontogenetic development, digestive enzymatic activity and gene expression in redseabream (Pagrus major). Aquaculture. 512. article:734283, 2019

https://doi.org/10.1016/j.aquaculture.2019.734283

56. Waqalevu, V., Honda, A., Dossou, S., Tran, NDK., Matsui, H.,Mzengereza, K., Hanlin, L., Ishikawa, M., Shiozaki, K., Kotani, T., Effect of oil enrichment on Brachionus plicatilis rotifer and first feeding red seabream (Pagrus major) and Japanese flounder (Paralichthys olivaceus). Aquaculture., 510, 73-83, 2019

https://doi.org/10.1016/j.aquaculture.2019.05.039

55. Waqalevu, VP., Matusi, H., Honda, A., Dossou, S., Yamamoto, A., Shiozaki, K., Kotani, T., Enrichment effect on two Brachionus plicatilis sp. complex morphotypes fed three nutritional enrichment diets. Aquacult. Sci. 67, 139-155, 2019

https://doi.org/10.11233/aquaculturesci.67.139

54. Hayasaka, O., Takeuchi, Y., Shiozaki, K., Anraku, K., Kotani, T. Green light irradiation during sex differentiation induces female-to-male sex reversal in the medaka Oryzias latipes. Sci. Rep. 9, article No.2383, 2019

https://doi.org/10.1038/s41598-019-38908-w

53. 塩崎一弘, 大石一樹, 本田晃伸：魚類シアリダーゼの生理機能とその魚種間における多様性. Trend. Glycosci. Glycotech. 31, J7-J14, 2019

https://doi.org/10.4052/tigg.1518.1J

52. Shiozaki, K., Oishi, K., Honda,K. Functional characterization of fish sialidases and their diversity among different orders. Trend. Glycosci. Glycotech. 31, E7-E13, 2019

https://doi.org/10.4052/tigg.1518.1E

2018

51. Waqalevu, VP., Honda, A., Matsui, H., Shiozaki, K., Kotani, T. Proteolytic digestive enzyme response in Japanese flounder larve Paralichthys olivaceus red two types of rotifers Brachionus plicatilis species complex. Fish Sci., 84, 1037-1049, 2018

https://doi.org/10.1007/s12562-018-1241-2

50. Matsumoto, M., Amer, MT., Araki, K., Nishitani, A., Hayashi, K., Takeuchi, Y., Shiozaki, K., Yamamoto, A., Amberjack Seriola dumerili interleukin-10 negatively suppresses host cell-mediated immunity. Fish. Sci., 84, 857-867, 2018

https://doi.org/10.1007/s12562-018-1223-4

49. Matsumoto, M., Araki, K., Nishimura, S., Kuriyama, H., Nakanishi, T., Shiozaki, K., Takeuchi, Y., Yamamoto, A. Adjuvant effect in aquaculture fish of cell-wall glycolipids isolated from acid-fast bacteria. Dev. Comp. Immunol., 85, 142-149, 2018

https://doi.org/10.1016/j.dci.2018.04.012

48. Honda, A., Chigwechokha, P., Kamada-Futagami, Y., Komatsu, M., Shiozaki, K., Unique nuclear localization of Nile tilapia (Oreochromis niloticus) Neu4 sialidase is regulated by nuclear transport receptor importin alpha/beta. Biochimie., 142, 94-104, 2018

https://doi.org/10.1016/j.biochi.2018.04.003

47. Miyagi, T., Takahashi, K., Yamamoto, K., Shiozaki, K., Yamaguchi, K., Biological and Pathological Roles of Ganglioside Sialidases. Prog. Mol. Biol. Transl. Sci., 156, 121-150, 2018.

https://doi.org/10.1016/bs.pmbts.2017.12.005

2017

46. Matsumoto, M., Araki, K., Hayashi, K., Takeuchi, Y., Shiozaki, K., Suetake, H., Yamamoto, A., Adjuvant effect of recombinant interleukin-12 in the Nocardiosis formalin-killed vaccine of the amberjack Seriola dumerili. Fish Shellfish Immunol., 67, 263-269, 2017

https://doi.org/10.1016/j.fsi.2017.06.025

45. Takumi, S., Shimono, T., Ikema, S., Hotta, Y., Chigwechokha, P., Shiozaki, K., Sugiyama, Y., Hashimoto, M., Furukawa T., Komatsu, M., Overexpression of carboxylesterase contributes to the attenuation of cyanotoxin microcystin-LR toxicity. Comp. Biochem. Physiol. C Toxicol. Pharmacol., 194, 22-27, 2017

https://doi.org/10.1016/j.cbpc.2017.01.008

44. Ryuzono, S., Takase, R., Kamada, Y., Ikenaga, T., Chigwechokha, P., Komatsu, M., Shiozaki. K., Suppression of Neu1 sialidase delays the absorption of yolk sac in medaka (Oryzias latipes) accompanied with the accumulation of alpha 2-3 sialo-glycoproteins. Biochimie, 135, 63-71, 2017

https://doi.org/10.1016/j.biochi.2017.01.008

43. Shiozaki, K., Yoshikawa, M., Kiguchiya, S., Ikeda, A., Kamada, Y., Chigwechokha, P., Komatsu, M., Matrix metalloproteinase-7 inhibitory activity of lipid extract from dwarf gulper shark (Centrophorus atromarginatus) through down-regulation of gene transcription. J. Funct. Food., 30, 90-96, 2017

https://doi.org/10.1016/j.jff.2017.01.013

42. Shinyoshi, S., Kamada, Y., Matsusaki, K., Chigwechokha, P., Tepparin, S., Araki, K., Komatsu, M., Shiozaki, K., Naringenin suppresses Edwardsiella tarda infection in GAKS cells by NanA sialidase inhibition. Fish Shellfish Immunol., 61, 86-92, 2017

https://doi.org/10.1016/j.fsi.2016.12.018

2016

41. Yoshinaga, A., Kajiya, N., Oishi, K., Kamada, Y., Ikeda, A., Chigwechokha, P., Kibe, T., Kishida, M., Kishida, S., Komatsu, M., Shiozaki, K., NEU3 inhibitory effect of naringin suppresses cancer cell growth by attenuation of EGFR signaling through GM3 ganglioside accumulation. Eur. J. Pharmacol., 782, 21-29, 2016

https://doi.org/10.1016/j.ejphar.2016.04.035

40. Kanouchi, H., Kakimoto, T., Nakano, H., Nakai, Y., Shiozaki, K., Akikoka, K., Otomaru, K., Matsumoto, M., Nagano, M., The brewed rice vinegar Kurozu increases HSPA1A expression and ameliorates cognitive dysfunction in aged P8 mice. PLos One, 4, e0150769, 2016

https://doi.org/10.1371/journal.pone.0150796

39. Shiozaki, K., Harasaki, Y., Fukuda, M., Yoshinaga, A., Ryuzono, S., Chigwechokha, P., Komatsu M., Miyagi, T. Positive regulation of myoblast differentiation by medaka Neu3b sialidase through ganglioside desialylation. Biochimie, 123, 65-72, 2016

https://doi.org/10.1016/j.biochi.2016.01.010

38. Funahashi, A., Komatsu, M., Furukawa, T., Yoshizono, Y., Yoshizono, H., Orikawa, Y., Takumi, S., Shiozaki, K., Hayashi, S., Kaminishi, Y., Itakura, T., Eel green fluorescent protein is associated with resistance to oxidative stress. Comp. Biochem. Physiol. C, 181–182, 35–39, 2016

https://doi.org/10.1016/j.cbpc.2015.12.009

37. Ryuzono, S., Takase, R., Oishi, K., Ikeda, A., Chigwechokha, P., Funahashi, A., Komatsu, M., Miyagi, T., Shiozaki, K., Lysosomal localization of Japanese medaka (Oryzias latipes) Neu1 sialidase and its highly conserved enzymatic profiles with human. Gene, 575, 513-523, 2016

https://doi.org/10.1016/j.gene.2015.09.028

2015

36. Chigwechokha, P., Tabata, M., Shinyoshi, S., Oishi, K., Araki, K., Komatsu, M., Itakura, T., Shiozaki, K., Recombinant sialidase NanA (rNanA) cleaves alpha 2-3-linked sialic acid of host cell surface N-linked glycoprotein to promote Edwardsiella tarda infection. Fish Shellfish Immunol., 47, 34-45, 2015

https://doi.org/10.1016/j.fsi.2015.08.015

35. Ikema, S., Takumi, S., Maeda, Y., Kurimoto, T., Bohda, S., Chigwechokha, P., Sugiyama, Y., Shiozaki, K., Furukawa, T., Komatsu M., Okadaic acid is taken-up into the cells mediated by human hepatocytes transporter OATP1B3. Food Chem Toxicol., 83, 229-236, 2015

https://doi.org/10.1016/j.fct.2015.06.006

34. Shiozaki, K., Takahashi, K., Hosono, M., Yamaguchi, K., Hata, K., Shiozaki, M., Bassi, R., Prinetti, A., Sonnino, S., Nitta, K., Miyagi, T., Phosphatidic acid-mediated activation and translocation to the cell surface of sialidase NEU3, promoting signaling for cell migration. FASEB J., 29, 2099-2111, 2015

https://doi.org/10.1096/fj.14-262543

33. Yamamoto, K., Takahashi, K., Shiozaki, K., Yamaguchi, K., Moriya, S., Hosono, M., Shima, H., Miyagi, T., Potentiation of epidermal growth factor -mediated oncogenic transformation by sialidase NEU3 leading to Src activation. PLoS One, 10, e0120578, 2015

https://doi.org/10.1371/journal.pone.0120578

32. Takumi, S., Ikema, S., Hanyu, T., Shima, Y., Kurimoto, T., Shiozaki, K., Sugiyama, Y., Park, H., Ando, S., Furukawa, T., Komatsu, M., Naringin attenuates the cytotoxicty of hepatotoxin microcystin-LR by the curious mechanisms to OATP1B1- and OATP1B3-expressing cells. Environ Toxicol Pharmacol, 39, 974-981, 2015

https://doi.org/10.1016/j.etap.2015.02.021

31. Hata, K., Tochigi, T., Sato, I., Kawamura, S., Shiozaki, K., Wada, T., Takahashi, K., Moriya, S., Yamaguchi, K., Hosono, M., Miyagi, T., Increased sialidase activity in serum of cancer patients: identification of sialidase and inhibitor activities in human serum. Cancer Sci, 106, 373-389, 2015

https://doi.org/10.1111/cas.12627

30. Miyagi, T., Takahashi, K., Shiozaki, K., Yamaguchi, K., Hosono, M., Plasma membrane-associated sialidase confers cancer initiation, promotion and progression. Adv. Exp. Med. Biol, 842, 139-45, 2015

https://doi.org/10.1007/978-3-319-11280-0_9

29. Ikeda, A., Ichino, H., Kiguchiya, S., Chigwechokha, P., Komatsu, M., Shiozaki, K., Evaluation and identification of potent angiotensin-I converting enzyme inhibitory peptide derived from dwarf gulper shark (Centrophorus atromarginatus). J. Food Process Pres, 39, 107-115 2015

https://doi.org/10.1111/jfpp.12210

2014

28. Takano, H., Takumi, S., Ikema, S., Mizoue, N., Hotta, Y., Shiozaki, K., Sugiyama, Y., Furukawa, T., Komatsu, M., Microcystin-LR Induces Anoikis Resistance to the Hepatocyte Uptake Transporter OATP1B3-expressing Cell Lines. Toxicology, 326, 53-61, 2014

https://doi.org/10.1016/j.tox.2014.10.003

27. Chigwechokha, P., Komatsu, M., Itakura, T., Shiozaki, K., Nile Tilapia Neu3 sialidases: molecular cloning, functional characterization and expression in Oreochromis niloticus. Gene, 552, 155-64, 2014

https://doi.org/10.1016/j.gene.2014.09.029

26. Shiozaki, K., Ryuzono, S., Matsushita, N., Ikeda, A., Takeshita, K., Chigwechokha, P., Komatsu, M., Miyagi, T.,Molecular cloning and biochemical characterization of medaka (Oryzias latipes) lysosomal neu4 sialidase Fish Physiol Biochem, 40, 1461-1472, 2014

https://doi.org/10.1007/s10695-014-9940-9

2013

25. 高橋耕太, 塩崎一弘, 宮城妙子：シアリダーゼによる細胞接着の制御．生体の化学, 64, 273-278, 2013

https://doi.org/10.11477/mf.2425101452

24. Komatsu, M., Ichiyama, N., Kurimoto, T., Takumi, S., Shiozaki, K., Sugiyama, Y., Furukawa, T., Ando, S., Itonori, S., Saito, H., Ceramide aminoethylphosphonate from jumbo flying squid Dosidicus gigas attenuates the toxicity of cyanotoxinmicrocystin-LR. Fish. Sci, 79, 313-320, 2013

https://doi.org/10.1007/s12562-012-0593-2

23. Shiozaki, K., Takeshita, K., Ikeda, M., Ikeda, A., Harasaki, Y., Komatsu, M., Yamada, S., Yamaguchi, K., Miyagi, T., Molecular cloning and biochemical characterization of two novel Neu3 sialidases, neu3a and neu3b, from medaka (Oryzias latipes). Biochimie, 95, 280-289, 2013

https://doi.org/10.1016/j.biochi.2012.09.026

2012

22. Yamaguchi, K., Shiozaki, K., Moriya, S., Koseki K., Wada T., Tateno, H., Sato, I., Asano, M., Iwakura, Y., Miyagi, T., Reduced susceptibility to colitis-associated colon carcinogenesis in mice lacking plasma membrane-associated sialidase. PLos One, 7, e41132, 2012

https://doi.org/10.1371/journal.pone.0041132

21. Miyagi, T., Takahashi, K., Hata, K., Shiozaki, K., Yamaguchi, K., Sialidase significance for cancer progression. Glycoconj. J., 29, 567-577, 2012

https://doi.org/10.1007/s10719-012-9394-1

20. Takahashi, K., Mitoma, J., Hosono, M., Shiozaki, K., Sato, C., Yamaguchi, K., Kitajima, K., Higashi, H., Nitta, K., Shima, H., Miyagi, T., Sialidase NEU4 hydrolyzes polysialic acids of neural cell adhesion molecules and negatively regulates neurite formation by hippocampal neurons. J. Biol. Chem., 287, 14816-14826, 2012

https://doi.org/10.1074/jbc.M111.324186

19. Miyagi, T., Takahashi, K., Moriya, S., Hata, K., Yamamoto, K., Wada, T., Yamaguchi, K., Shiozaki, K., Altered expression of sialidases in human cancer. Adv. Exp. Med. Biol, 749, 257-267, 2012

https://doi.org/10.1007/978-1-4614-3381-1_17

18. Oku, T., Ando, S., Tsai, H., Yamashita, Y.,Ueno, H., Shiozaki, K., Nishi, R., Yamada, S., Purification and identification of two carnosine-cleaving enzymes,carnosine dipeptidase I and Xaa-methyl-His dipeptidase, from Japanese eel(Anguilla japonica). Biochimie, 94, 1281-1290, 2012

https://doi.org/10.1016/j.biochi.2012.02.016

2011

17. Shiozaki, K., Yamaguchi, K., Takahashi, K., Moriya, S., Miyagi, T., Regulation of sialyl lewis antigen expression in colon cancer cells by sialidase NEU4. J Biol Chem, 286, 21052-21061, 2011

https://doi.org/10.1074/jbc.M111.231191

16. Oku, T., Ando, S., Hayakawa, T., Baba, K., Nishi, R., Shiozaki, K., Yamada. S., Purification and identification of a novel primitive secretory enzyme catalyzing the hydrolysis of imidazole-related dipeptides in the jawless vertebrate Lethenteron reissneri. Peptides, 32, 648-655, 2011

https://doi.org/10.1016/j.peptides.2011.01.008

2010

15. Shiozaki, K., Shiozaki, M., Masuda, J., Yamauchi, A., Ohwada, K., Nakano, T., Yamaguchi, T., Saito, T., Muramoto, K., Sato, M., Identification of oyster-derived hypotensive peptide acting as angiotensin I converting enzyme inhibitor. Fish Sci, 76, 865-872, 2010

https://doi.org/10.1007/s12562-010-0264-0

2009

14. Shiozaki, K., Koseki, K., Yamaguchi, K., Shiozaki, M., Narimatsu, H., Miyagi, T., Developmental change of sialidase Neu4 expression in murine brain and its involvement in the regulation of neuronal cell differentiation. J Biol Chem, 284, 21157-21164, 2009

https://doi.org/10.1074/jbc.M109.012708

13. Shiozaki, K., Yamaguchi, K., Sato, I., Miyagi, T., Plasma membrane-associated sialidase (NEU3) promotes formation of colonic aberrant crypt foci in azoxymethane-treated transgenic mice. Cancer Sci, 100, 588-594, 2009

https://doi.org/10.1111/j.1349-7006.2008.01080.x

12. Uemura, T., Shiozaki, K., Yamaguchi, K., Miyazaki, S., Satomi, S., Kato, K., Sakuraba, H. Miyagi, T., Contribution of sialidase NEU1 to suppression of metastasis of human colon cancer cells through desialylation of integrin beta4. Oncogene, 28, 1218-1229, 2009

https://doi.org/10.1038/onc.2008.471

2008

11. Miyagi, T., Wada, T., Yamaguchi, K., Shiozaki, K., Sato, I., Kakugawa, Y., Yamanami, H., Fujiya, T., Human sialidase as a cancer marker. Proteomics, 8, 3303-3311, 2008

https://doi.org/10.1002/pmic.200800248

10. Miyagi, T., Wada, T., Yamaguchi, K., Hata, K., Shiozaki, K., Plasma membrane- associated sialidase as a crucial regulator of transmembrane signaling. J Biochem, 144, 279-285, 2008

https://doi.org/10.1093/jb/mvn089

2007

9. Wada, T., Hata, K., Yamaguchi, K., Shiozaki, K., Koseki, K., Moriya, S., Miyagi, T., A crucial role of plasma membrane-associated sialidase in the survival of human cancer cells. Oncogene, 26, 2483-2490, 2007

https://doi.org/10.1038/sj.onc.1210341

8. Yamanami, H., Shiozaki, K., Wada, T., Yamaguchi, K., Uemura, T., Kakugawa, Y., Hujiya, T., Miyagi. T., Down-regulation of sialidase NEU4 may contribute to invasive properties of human colon cancers. Cancer Sci, 98, 299-307, 2007

https://doi.org/10.1111/j.1349-7006.2007.00403.x

7. 宮城妙子, 上村卓嗣, 塩崎一弘, 山口壹範 ：癌の浸潤・転移と糖鎖．実験医学, 25, 1042-1048, 2007 Journal Website

2006

6. Shiozaki, K., Fujii, A., Nakano, T., Yamaguchi, T., Sato, M., Inhibitory effects of hot water extract of the stevia stem on the contractile response of the smooth muscle of the guinea pig ileum. Biosci Biotechnol Biochem, 70, 489-494, 2006

https://doi.org/10.1271/bbb.70.489

5. Sato, M., Tao, Z., Shiozaki, K., Nakano, T., Yamaguchi, T., Yokoyama, T., Kanno, N., Nagahisa, E., A simple and rapid method for the analysis of fish histamine by paper electrophoresis. Fish Sci, 72, 889-892, 2006

https://doi.org/10.1111/j.1444-2906.2006.01232.x

2005

4. Yamaguchi, K., Hata, K., Koseki, K., Shiozaki, K., Akita, H., Wada, T., Moriya, S., Miyagi, T., Evidence for mitochondrial localization of a novel human sialidase (NEU4). Biochem J, 390, 85-93, 2005

https://doi.org/10.1042/BJ20050017

2004

3. Shiozaki, K., Nakano, T., Yamaguchi, T., Sato, M., Sato, N., The protective effect of stevia extract on the gastric mucosa of rainbow trout Oncorhynchus mykiss (Walbaum) fed dietary histamine. Aquacult Res, 35, 1421-1428, 2004

https://doi.org/10.1111/j.1365-2109.2004.01164.x

2003

2. Shiozaki, K., Nakano, T., Yamaguchi, T., Sato, M., Metabolism of exogenous histamine in rainbow trout (Oncorhynchus mykiss). Fish Physiol Biochem, 29, 289-295, 2003

https://doi.org/10.1007/s10695-004-9295-8

2002

1. Sato, M., Tao, Z., Shiozaki, K., Nakano, T., Yamaguchi, T., Kumagai, T., Yokoyama, T., Kanno, N., Nagahisa, E., A rapid method for histamine analysis of seafoods by paper electrophoresis. ITE lett Batt New technol Med, 3, 68-70, 2002

https://jglobal.jst.go.jp/en/detail?JGLOBAL_ID=200902147850775993

著書

2016

塩崎一弘. 鹿児島県近海に生息するサメ類の有効利用法の開発. (鮫島奈々美, 叶内宏明, 塩崎一弘, 吉崎由美子編）, 鹿児島の食環境と健康食材, 南方新社., 2016, pp.155-172.

https://ci.nii.ac.jp/ncid/BB21273556

2015

Miyagi, T., Takahashi, K., Shiozaki, K., Yamaguchi, K. Mammalian Sialidase and Tumor Development. (Eds. T, Suzuki., T, Ohtsubo., N, Taniguchi), Sugar Chains, Springer., 2015, pp. 159–176.

https://doi.org/10.1007/978-4-431-55381-6_10

2014

Miyagi, T., Takahashi, K., Shiozaki, K., Yamaguchi, K. Mammalian Sialidase Assays. (Eds. T, Endo., PH, Seeberger., GW, Hart., CH, wong, N, Taniguchi), Glycoscience:Biology and Medicine, Springer., 2014, pp. 1395-1402.

https://doi.org/10.1007/978-4-431-54836-2_189-1